Cannabis For Chronic Pain


This week, KannAInsight features a new study on the effect of cannabis in patients with chronic pain caused by fibromyalgia.

Four different varieties of inhaled cannabis with varying THC and CBD content were tested in fibromyalgia patients. Pain tolerance and relief was assessed during the first few hours after a single treatment.

Cannabis containing high THC content was the most effective in increasing pressure pain tolerance. Patients also experienced a reduction in spontaneous pain after treatment with the high THC/high CBD variety of cannabis. When CBD was given without THC, the effects were no different from placebo. For all treatments, some side effects were observed, such as sore throat, cough, dizziness, and nausea, but all were considered mild. However, it was noted that most patients disliked the feeling of a drug high after inhalation.

Based on the results of this study, further research is warranted to determine the safety and efficacy of long-term treatment with cannabis on chronic pain in fibromyalgia patients.

Citation: van de Donk T, Niesters M, Kowal MA, Olofsen E, Dahan A, van Velzen M. An experimental randomized study on the analgesic effects of pharmaceutical-grade cannabis in chronic pain patients with fibromyalgia. Pain. 2018 Dec 20